San Francisco 49ers: next games 
San Francisco 49ers 2025 Schedule
National Football League · NFC Record 12-5
Regular season
Record 12-5
- ScoreboardWeek 1SEP72025Away49ersat
Seattle SeahawksW17–131-0 - ScoreboardWeek 2SEP142025Away49ersat
New Orleans SaintsW26–212-0 - ScoreboardWeek 3SEP212025Home49ersvs
Arizona CardinalsW16–153-0 - ScoreboardWeek 4SEP282025Home49ersvs
Jacksonville JaguarsL21–263-1 - ScoreboardWeek 5OCT22025Away49ersat
Los Angeles RamsW26–234-1 - ScoreboardWeek 6OCT122025Away49ersat
Tampa Bay BuccaneersL19–304-2 - ScoreboardWeek 7OCT192025Home49ersvs
Atlanta FalconsW20–105-2 - ScoreboardWeek 8OCT262025Away49ersat
Houston TexansL15–265-3 - ScoreboardWeek 9NOV22025Away49ersat
New York GiantsW34–246-3 - ScoreboardWeek 10NOV92025Home49ersvsLos Angeles RamsL26–426-4
- ScoreboardWeek 11NOV162025Away49ersatArizona CardinalsW41–227-4
- ScoreboardWeek 12NOV242025Home49ersvs
Carolina PanthersW20–98-4 - ScoreboardWeek 13NOV302025Away49ersat
Cleveland BrownsW26–89-4 - Week 14Bye week
- ScoreboardWeek 15DEC142025Home49ersvs
Tennessee TitansW37–2410-4 - ScoreboardWeek 16DEC222025Away49ersat
Indianapolis ColtsW48–2711-4 - ScoreboardWeek 17DEC282025Home49ersvs
Chicago BearsW42–3812-4 - ScoreboardWeek 18JAN32026Home49ersvsSeattle SeahawksL3–1312-5
Postseason
Record 1-1
- ScoreboardJAN112026Away49ersat
Philadelphia EaglesW23–19 - ScoreboardJAN172026Away49ersatSeattle SeahawksL6–41
Preseason
- ScoreboardAUG92025Home49ersvs
Denver BroncosL9–30 - ScoreboardAUG162025Away49ersat
Las Vegas RaidersW22–19 - ScoreboardAUG232025Home49ersvs
Los Angeles ChargersW30–23